Nubiyota

Microbial Ecosystem Therapeutics

NuBiyota’s Microbial Ecosystem Therapeutics (MET) technology utilizes the microbiota derived from an individual “super donor”. This microbiota demonstrated efficacy across several different indications in the form of FMT therapeutics.

NuBiyota’s CMC platform is based on the creation of a strain bank of beneficial microbes isolated and purified from this donor, which have been carefully curated and stored. This ensures a highly standardized composition of microbes across the entire production process.

NuBiyota’s proprietary approach includes a unique culturing process enabling the creation of multi-strain formulations.

NuBiyota has focused on developing the optimal combination of microbes for the restoration of ecosystem function, encapsulating multi-strain compositions at production scales, which uses methods developed to adhere to GMP standards.

  • 01

    Donor Selection

    Extensive search for healthy donor that shows sample efficacy across different indications suitable for FMT.

  • 02

    Strain Bank Establishment

    Remove pathogens
    Select optimal strains
    Isolate, purify and identify strains

  • 03

    Culture

    Culture strains.
    Methods to enhance growth of more fastidious strains.
    Create defined complex community.

  • 04

    Lyophilization

    Freeze and lyophilize. Microbes are stored in a freeze-dried state to ensure functionality.

  • 05

    Encapsulation of ecosystems

    Focus on ecosystem functionality.
    Develop multiple generations for various indications.

  • 06

    Scale Production

    Standardize product.
    Regulatory approval.

Consistent, Scalable and Effective

We have developed several drug products, each from an individual ‘super-donor’ to preserve ecosystem function

We have been able to culture even difficult-to-grow strains to create unique compositions with high efficacy

Multi-strain approach for complete microbiome restoration

We use a standardized process to ensure consistency and reproducibility

Our products undergo strict safety profiling and are scalable to GMP production standards

We produce high quality drugs with optimal stability

We use a standardized process to ensure consistency and reproducibility

Our products undergo strict safety profiling and are scalable to GMP production standards

We produce high quality drugs with optimal stability